'The Departed' (2006)

Song: "Shipping Up to Boston" by The Dropkick Murphys
Why We Love It: Here's Scorsese again, showing he's still got enough zip on his fastball to turn a music cue into a moment of cultural significance. Where would Jonathan Papelbon and the Red Sox be without 'The Departed' bringing 'Shipping Up to Boston' into the zeitgeist?